{"id":3405,"date":"2016-05-05T10:05:38","date_gmt":"2016-05-05T10:05:38","guid":{"rendered":"http:\/\/dweb.pfsgrupo.com\/hospitalcardona\/blog\/2019\/07\/26\/nanoparticulas-contra-el-asma\/"},"modified":"2016-05-05T10:05:38","modified_gmt":"2016-05-05T10:05:38","slug":"nanoparticulas-contra-el-asma","status":"publish","type":"post","link":"https:\/\/riberasalud.com\/juan-cardona\/2016\/05\/05\/nanoparticulas-contra-el-asma\/","title":{"rendered":"Nanopart\u00edculas contra el asma","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"
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Publicado por <\/span>Hospital Juan Cardona el 5 de mayo de 2016 11:17:00 CEST<\/div>\n

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Como si se tratara de un caballo de Troya<\/span>, un equipo de cient\u00edficos ha usado unas\u00a0nanopart\u00edculas contra el asma<\/span>, una tecnolog\u00eda que podr\u00eda emplearse tambi\u00e9n contra alergias alimentarias, por ejemplo a los cacahuetes.
\nEn un nuevo enfoque para tratar el asma y las alergias, la nanopart\u00edcula oculta en su interior un al\u00e9rgeno pero su aspecto externo no es amenazador por lo que es capaz de convencer al sistema inmunitario para que no la ataque, seg\u00fan el estudio de la Northwestern University (EU)<\/span> <\/strong>El estudio, indica que de esta manera se suprime a largo plazo la reacci\u00f3n al\u00e9rgica que se produce en las v\u00edas a\u00e9reas ante un agente extra\u00f1o y as\u00ed se previenen los ataques de asma. Esta tecnolog\u00eda, seg\u00fan los expertos, puede tambi\u00e9n emplearse en las alergias causadas por los alimentos y, de hecho, la nanopart\u00edcula est\u00e1 siendo ya probada en un modelo con ratones al\u00e9rgicos a los cacahuetes, que es similar a la que sufren los humanos.<\/p>\n

El autor principal del estudio Stephen Miller de la Nortwestern University<\/span> explic\u00f3 que este descubrimiento \u00absupone una forma a largo plazo novedosa, segura y eficaz para tratar y potencialmente ‘curar’ a pacientes que sufren alergias respiratoria y alimenticias que pueden amenazar su vida\u00bb. Esta es la primera vez que este m\u00e9todo para crear tolerancia en el sistema inmunitario se emplea en alergias, aunque ya se est\u00e1 usando en test precl\u00ednicos para enfermedades autoinmunes<\/span>, entre ellas la esclerosis m\u00faltiple, adem\u00e1s de para las dolencias cel\u00edacas. Se trata de \u00abun tratamiento universal\u00bb pues dependiendo de la alergia que se quiera eliminar es posible cargar la nanopart\u00edcula con polen de ambros\u00eda o con prote\u00edna de cacahuete, seg\u00fan explic\u00f3 el experto.<\/p>\n

La nanopart\u00edcula que se convertir\u00e1 en caballo de Troya para ‘enga\u00f1ar’ al sistema inmunitario y librarse de su ataque est\u00e1 compuesta de un biopo\u00edmero llamado PLGA -aprobado por la Administraci\u00f3n de Alimentos y Medicamentos de Estados Unidos- que incluye \u00e1cido l\u00e1ctico y \u00e1cido gloc\u00f3lico. Cuando la nanopart\u00edcula cargada con el al\u00e9rgeno se inyecta en el torrente sangu\u00edneo de un rat\u00f3n su sistema inmunitario no reacciona pues la part\u00edcula parece un desecho inocuo el cual es eliminado por un macr\u00f3fago -un tipo de gl\u00f3bulo blanco que fagocita el material extra\u00f1o en el cuerpo-. \u00abLa c\u00e9lula aspiradora (en referencia al macr\u00f3fago) presenta el al\u00e9rgeno o el ant\u00edgeno al sistema inmunitario diciendo: ‘no os preocup\u00e9is esto es de aqu\u00ed'\u00bb, por lo que este detiene su ataque y se normaliza, explic\u00f3 Miller. Durante el experimento los roedores fueron tratados para ser al\u00e9rgicos a la prote\u00edna de la c\u00e1scara de huevo, por lo que ya ten\u00edan en la sangre anticuerpos y cuando volvieron a exponerlos a esta tuvieron una reacci\u00f3n al\u00e9rgica parecida al asma. Sin embargo, tras ser inyectarles la nanopart\u00edcula no presentaron ninguna respuesta al\u00e9rgica. Habr\u00e1 que esperar para sber si \u00e9sta es la soluci\u00f3n definitiva contra el asma y las alergias alimentarias, pero la consideramos una muy buena noticia en el campo de la investigaci\u00f3n m\u00e9dica.<\/p>\n

Conozca otros avances m\u00e9dicos de \u00faltima generaci\u00f3n aqu\u00ed.<\/a><\/p>\n


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Hayan unas nanopart\u00edculas contra el asma que podr\u00eda emplearse tambi\u00e9n en el tratamiento de alergias. Inf\u00f3rmese aqu\u00ed.<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-3405","post","type-post","status-publish","format-standard","hentry","category-noticias-del-hospital-juan-cardona"],"yoast_head":"\nNanopart\u00edculas contra el asma - Hospital Ribera Juan Cardona<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/riberasalud.com\/juan-cardona\/2016\/05\/05\/nanoparticulas-contra-el-asma\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nanopart\u00edculas contra el asma - Hospital Ribera Juan Cardona\" \/>\n<meta property=\"og:description\" content=\"Hayan unas nanopart\u00edculas contra el asma que podr\u00eda emplearse tambi\u00e9n en el tratamiento de alergias. 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