Celiac disease gluten intolerance test (genetic and serological)
An analysis that combines genetic and serological markers to help you find out if you have a genetic predisposition to celiac disease and if your body shows signs compatible with the disease.
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Evaluate genetic predisposition to celiac disease (HLA DQ2/DQ8).
Detects antibodies associated with celiac disease.
It helps to identify active celiac disease or future risk of developing it.
Simple test using blood analysis.
Clear report to guide the diagnosis with your doctor.
What is the celiac disease test?
El celiac disease test It combines genetic analysis and serological testing to detect:
- It tienes genetic predisposition to develop celiac disease (HLA DQ2/DQ8 genes).
- If your body produces specific antibodies that rise when there is an immune response to gluten.
This study is useful both for people with compatible digestive symptoms and for relatives of celiac patients or people who already follow a gluten-free diet and need a complete evaluation.
What is the purpose of this study?
The celiac test is used to:
✓ Evaluate genetic predisposition (It doesn't change over the years).
✓ Detect active celiac disease through specific antibodies.
✓ Rule out the disease when the results are negative.
✓ Complement other digestive studies.
✓ To guide your doctor towards a more accurate diagnosis.
It is especially useful if you have already started a gluten-free diet, because the genetic study It is not affected by diet.
What symptoms might suggest celiac disease?
Celiac disease can manifest with a wide variety of symptoms. The test is useful if you experience:
Diarrhea, constipation, or alternating.
Frequent bloating and gas.
Unexplained weight loss.
Recurring abdominal pain.
Iron deficiency anemia that does not improve.
Skin eruptions consistent with dermatitis herpetiformis.
Persistent fatigue.
Difficulty absorbing nutrients.
It is also recommended for first-degree relatives of people with celiac disease.
What does the celiac disease test include?
Genetic study (HLA DQ2/DQ8)
Evaluate whether you have a genetic predisposition. A negative result virtually rules out celiac disease for life.
Serological study
Analyzes specific antibodies associated with celiac disease (the most commonly used by laboratories):
- Anti-transglutaminase IgA
- Anti-endomysium IgA
- (If IgA deficiency is suspected, it can be supplemented with IgG isotypes)
Analyzes specific antibodies associated with celiac disease (the most commonly used by laboratories):
- Anti-transglutaminase IgA
- Anti-endomysium IgA
- (If IgA deficiency is suspected, it can be supplemented with IgG isotypes)
Your center can adapt the battery according to protocols.
How is the test performed?
It is a safe, painless and comfortable procedure.
Step 1:
Test request
You can request the study directly at your nearest Ribera Lab center.
Step 2:
Blood draw
A simple extraction is performed at one of the available centers.
Step 3:
Laboratory analysis
The laboratory evaluates your DNA (genetics) and your antibodies (serology).
Step 4:
Results and report
You will receive a clear and structured report to help you understand your results and discuss them with your doctor.
Interpretation of results
Genetic results
- Negative
You have no genetic predisposition: very low probability of celiac disease. - Impact
You have a predisposition: it doesn't mean you have celiac disease, just an increased risk.
Serological results
- Elevated antibodies:
possible active celiac disease. - Normal antibodies:
It reduces the probability, but it depends on your current diet and symptoms.
Your doctor will integrate the data with your medical history and, if necessary, may request additional tests (such as a duodenal biopsy).